Nutrient encapsulation in protein core polysaccharide shell bilayer emulsions
This novel core-shell emulsion system enhances micronutrient delivery using a protein matrix and phytosphingosine for improved bioavailability. Stabilized by xanthan gum, it protects nutrients and enhances intestinal transport, ideal for VMS applications.
Overview
The proposed technology is a novel core-shell emulsion aimed at improving micronutrient delivery. It features a protein matrix of zein and casein that encapsulates micronutrients and a permeability enhancer, phytosphingosine (PSS). This structure is homogenized within a vegetable oil phase and stabilized by an outer polysaccharide layer made of xanthan gum. The design ensures high loading capacity, protection from degradation, and enhanced bioavailability, making it highly suitable for vitamin-mineral-supplement (VMS) formats.
Technical specifications
- Core formulation: A protein matrix of zein/casein encapsulates micronutrients along with PSS to enhance permeability.
- Stabilization: The outer layer of xanthan gum provides stability to the emulsion.
- Enhanced transport: PSS synergistically enhances nutrient transport across the intestinal barrier.
- GRAS components: All components are Generally Recognized As Safe, ensuring compatibility with food applications.
Technology readiness level
The technology is currently at Technology Readiness Level 4. Initial development phases have focused on emulsion formulation and characterization. Future phases will involve in vitro performance validation to confirm the bio-enhancing effects and improved transport of micronutrients.
About Texas A&M University, College Station
Texas A&M University in College Station is a comprehensive public research university and the flagship of The Texas A&M University System, combining broad academic strengths with a strong applied‑research culture. Industry collaborates on the Texas A&M‑RELLIS campus—an integrated education, research and testing environment that supports large‑scale experimentation and proving grounds—and through the Texas A&M Transportation Institute’s facilities in Bryan‑College Station. A statewide extension network connects university expertise to companies and communities across all Texas counties, enabling rapid piloting and deployment. Research is supported by competitive federal funding from agencies such as NSF, NIH, DOE, USDA and DoD, alongside state and industry sponsorship. Texas A&M Innovation provides IP management, licensing and commercialization pathways across the system.
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