Heat-moisture resistant carriers for probiotic delivery in food processing
Innovative heat-moisture resistant carriers ensure viable probiotic delivery during food processing, utilizing plant glycoproteins, polyphenols, and polysaccharides for enhanced thermal stability and colon-targeted release.
Overview
This solution involves the development of heat-moisture resistant carriers that enhance the bioavailability of probiotics during high-temperature and moisture-intensive food processing. By using a novel combination of plant glycoproteins, polyphenols, and polysaccharides, these carriers are designed to protect probiotics from degradation during processing and ensure targeted delivery to the colon. This approach addresses the challenge of maintaining probiotic viability and enhancing their bioaccessibility to the gut microbiota.
Technical specifications
- Core technology: Microcarriers made from commercial plant glycoproteins complexed with polyphenols and polysaccharides.
- Features:
- Enhanced thermal resistance, suitable for processing temperatures over 80°C.
- Hydrophobic polysaccharides improve water exclusion and thermal degradation resistance.
- Glycoprotein-polyphenol interactions stabilize the structure and increase the melting point.
- Designed for continuous layer building to achieve optimal processing outcomes.
Technology readiness level
This technology is currently at TRL 3. The development focuses on evaluating heat and moisture-resistant microcarrier systems and prototyping probiotic gummies. The project aims to identify optimal components and processes for effective probiotic protection and delivery, with a projected validation timeframe of one year.
About Agency for Science, Technology and Research
ASTAR is Singapore’s national applied research agency, comprising a network of research institutes and shared facilities that drive innovation for the public and private sectors. Co-located campuses at one-north (Biopolis and Fusionopolis) link institutes with corporate R&D, startups, and investors for rapid collaboration. Industry programs provide access to advanced equipment with expert support, alongside multi‑party consortia and initiatives aligned with national priorities. The agency’s work is primarily supported through Singapore’s Research, Innovation & Enterprise programs via the National Research Foundation, with additional industry co‑funding. Commercialization is led by Accelerate, which manages IP, licensing, and venture creation.
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