Turgut Umur
caykur · Startup
Cardiac contractility modulators that lower the excess calcium sensitivity of heart muscle filaments in hypertrophic cardiomyopathy.
Co-developmentEarly-stage
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Updated Nov 2, 2026
Cardiovascular health covers the therapies, models and tissue resources used against heart and vascular disease. On Halo, the solutions cover genetic cardiomyopathy therapeutics, patient-derived cardiac cells and tissue banks, thrombosis and vascular models, and cardiometabolic prevention. Sign up to search the full network and post your specific need.
Genetic cardiomyopathy therapeutics
Turgut Umur
DY
University of Washington
Repurposes colchicine against MYH7 dilated cardiomyopathy by restoring the MEF2C-desmin axis.
In-development
RA
Houston Methodist · University
AAV9-delivered RNA interference against CSTF64, aimed at cutting cardiac fibrosis in heart failure.
In-development
Patient-derived cardiac cells and tissue banks
OB
Technion - Israel Institute of Technology · University
iPSC-derived cardiomyocytes carrying the patient's own cardiomyopathy mutation, for testing candidates.
In-development
RK
Fraunhofer Institute · University
A supply of hiPSC cardiomyocytes with known cardiomyopathy mutations, offered for collaboration.
In-development
RS
Sapphiros AiBio · Supplier
A bank of more than 85,000 human cell lines, including cardiomyopathy and Long QT lines.
In-development
Thrombosis and vascular models
UB
UC Berkeley · University
A vascularized heart-on-a-chip with immune cells that reproduces inflammatory cardiac injury, including weakened contraction and calcium handling.
In-development
PC
University of California, San Diego
A rabbit model of cerebral venous sinus thrombosis induced with ferric chloride.
In-development
Cardiometabolic prevention
UO
University of Cambridge
A systems-immunology workflow that found saracatinib reducing plaque inflammation and atherosclerosis in animal models.
In-development
Rodrigo Carrillo
Emory University
Uses systematic review and machine learning to optimize micronutrient profiles for cardiometabolic health.
Sponsored researchIn-development
Preclinical cardiovascular services
Avi Mayerhoff
University of Illinois Chicago
Preclinical rodent cardiovascular models run core-assisted, with echocardiography and hemodynamics.
Fee-for-service (self-serve)In-development
Avi Mayerhoff
University of Illinois Chicago
Standardized in-vivo metabolic phenotyping of rodent models, including cardiovascular studies.
Fee-for-service (full service)In-development
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Who is working on cardiovascular health
Organizations in cardiovascular health
Universities, startups, and suppliers with solutions in cardiovascular health.
Cardiovascular health organizations
Innovators in cardiovascular health
Researchers and inventors advancing cardiovascular health.
Cardiovascular health expertsAbout cardiovascular health
Cardiovascular health on Halo runs from the genetics of a named cardiomyopathy through to the preclinical models a program needs before it can test anything in people. On Halo it spans six groups, including genetic cardiomyopathy therapeutics, patient-derived cardiac cells and tissue banks, and thrombosis and vascular models.
Stage of development. Work on cardiovascular health on Halo comes mostly from university programs. 29% of the solutions are in market. Co-development and sponsored research are the usual partnering routes, and about 38% of the solutions that state terms offer pilot engagements.
Three trends in cardiovascular health on Halo
Therapies aimed at one mutation. These programs name the gene and not the syndrome. One repurposes colchicine against MYH7 dilated cardiomyopathy; another maps the kinome altered in LMNA-related disease. The work is narrower than heart failure and closer to the patients it would treat.
Patient-derived cardiac cells. Several groups now offer cardiomyocytes carrying a patient's own cardiomyopathy mutation, and one bank holds more than 85,000 human cell lines including Long QT. A candidate can be tested against the genotype it is meant for before any animal work.
Prevention through metabolism. A second cluster treats cardiovascular risk as a metabolic problem. One team screens postbiotics that block a gut microbial conversion tied to cardiac risk; another optimizes micronutrient profiles for cardiometabolic health using systematic review and machine learning.
372organizations
381solutions listed
74%from university labs
29%in market
Frequently asked questions
What is cardiovascular health?
Cardiovascular health covers the therapies, diagnostics and research models aimed at the heart and the blood vessels. It spans gene-specific cardiomyopathy programs, antithrombotic agents, cardiometabolic prevention, and the cell and tissue resources used to test any of them before a patient is involved. Pharmaceutical developers, device makers and academic cardiology groups do the work.
What are examples of cardiovascular health?
Five examples of cardiovascular health solutions on Halo include:
- Repurposes colchicine against MYH7 dilated cardiomyopathy by restoring the MEF2C-desmin axis. (University of Washington)
- iPSC-derived cardiomyocytes carrying the patient's own cardiomyopathy mutation, for testing candidates. (Technion - Israel Institute of Technology)
- An in vivo rabbit model for testing anti-thrombotic candidates against bleeding time. (University of Alberta)
- Uses systematic review and machine learning to optimize micronutrient profiles for cardiometabolic health. (Emory University)
- Preclinical rodent cardiovascular models run core-assisted, with echocardiography and hemodynamics. (University of Illinois Chicago)
What are the latest cardiovascular health innovations?
The most recently updated cardiovascular health solutions on Halo include:
- A systems-immunology workflow that found saracatinib reducing plaque inflammation and atherosclerosis in animal models. (University of Cambridge)
- A telehealth device that records a 3D vector ECG at home, built for remote monitoring of heart attack. (HeartBeam)
- A vascularized heart-on-a-chip with immune cells that reproduces inflammatory cardiac injury, including weakened contraction and calcium handling. (UC Berkeley)
Which companies and suppliers are developing cardiovascular health?
There are 372 organizations with cardiovascular health solutions on Halo, 74 of them universities and research institutions. Among them are caykur, University of Washington, and Houston Methodist. Most offer co-development or sponsored research. Sign up to see every organization working in the area and to send them your specific need.
How do I find cardiovascular health research partners?
Browsing cardiovascular health solutions on Halo is free. Sign up to search the full network and save the ones you want. Post your specific need to get exact matches. Organizations reply directly on the platform.
What are R&D teams looking for in cardiovascular health?
Over the past 12 months, R&D teams on Halo have posted these cardiovascular health needs:
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