Janus base nanoparticles carrying mRNA and gene editing tools to a chosen tissue.
In developmentStartup
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Updated Sept 30, 2026
Personalized medicine covers the delivery, dosing and profiling technologies that fit a treatment to one patient and not a population. On Halo, the solutions cover targeted gene and RNA delivery, printed and variable dosing, omics platforms for target selection, and patient-derived disease models. Sign up to search the full network and post your specific need.
Targeted gene and RNA delivery
Massachusetts Institute of Technology
Endosomolytic peptides that get mRNA out of the endosome and into the cytosol.
In developmentUniversity
KX
University of Michigan
A biodegradable cationic polymer vector with high transfection efficiency in vivo.
In developmentUniversity
University of Texas Southwestern Medical Center
Stabilized nanoparticles combining covalent and electrostatic binding for tissue-specific delivery.
In developmentUniversity
Ludwig-Maximilians Universität München
PBAE nanoparticles with targeting ligands attached by click chemistry, aimed organ by organ.
In developmentUniversity
AM
International Centre for Genetic Engineering and Biotechnology
Liver-directed gene therapy that has hepatocytes produce the missing Fabry enzyme.
In developmentUniversity
EG
Georgia State University
A lipid nanoparticle that inserts a recombinant uricase gene into liver cells.
In developmentUniversity
Non-viral peptide carriers generated for a given nucleic acid payload.
Co-developmentIn developmentStartup
Printed and variable dosing
JS
3D printed polypills combining several doses in one geometry, for variable-dose regimens.
In developmentStartup
RC
Université de Liège
Filaments loaded with active ingredients, so a printer can make the dose.
In developmentUniversity
MS
Universität für Bodenkultur Wien
Laser-powder bed fusion with responsive materials, for dose forms that release on a cue.
In developmentUniversity
Pharmaceutical-grade additive manufacturing expertise for custom dose forms.
Co-developmentIn marketStartup
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Who is working on personalized medicine
Organizations in personalized medicine
Universities, startups, and suppliers with solutions in personalized medicine.
Personalized medicine companies
Innovators in personalized medicine
Researchers and inventors advancing personalized medicine solutions.
Personalized medicine expertsAbout personalized medicine
Personalized medicine on Halo is practical and not conceptual: carriers that reach a named organ, printed dose forms that can be varied per patient, and omics platforms used to pick a target before any of that starts. On Halo it spans five groups, including targeted gene and RNA delivery, printed and variable dosing, and omics platforms for target selection.
Stage of development. Work on personalized medicine on Halo comes mostly from university programs. 91% are past proof of concept (TRL 4 or higher). Co-development and sponsored research are the usual partnering routes, and about 49% of the solutions that state terms offer pilot engagements.
Three trends in personalized medicine solutions on Halo
Printing the dose. Five solutions make the dose form itself variable. Polypills combine several drugs in one printed geometry, filaments carry the active ingredient into an FDM printer, and laser-powder bed fusion pairs with responsive materials. Personalization gets solved in manufacturing and not in the molecule.
Carriers aimed at one organ. The delivery cluster is organ-specific by design: liver-directed gene therapy for Fabry disease, PBAE nanoparticles with ligands clicked on for a chosen organ, and stabilized particles that combine covalent and electrostatic binding for tissue selectivity. Getting there is treated as the hard part.
Cells that carry the patient's mutation. Three groups supply iPSC-derived cardiomyocytes carrying specific cardiomyopathy mutations. A candidate can be run against the genotype it is meant for before any patient is involved, which is personalization at the testing stage and not the prescribing one.
753organizations
773solutions listed
62%from university labs
91%past proof of concept
Frequently asked questions
What are personalized medicine solutions?
Personalized medicine fits a treatment to one patient and not to a population, through targeting, dosing or profiling. It spans carriers aimed at a named organ, printed and variable dose forms, multi-omic platforms used to pick a target, and patient-derived cells used to test a candidate against the genotype it is meant for. Pharmaceutical developers and diagnostics companies are the buyers.
What are examples of personalized medicine solutions?
Five examples of personalized medicine solutions on Halo include:
- Janus base nanoparticles carrying mRNA and gene editing tools to a chosen tissue. (Eascra)
- 3D printed polypills combining several doses in one geometry, for variable-dose regimens. (InfraTrac, Inc)
- Multi-tissue profiling across genomics, transcriptomics, proteomics and metabolomics to find causal targets. (Washington University in St. Louis)
- iPSC cardiomyocytes carrying the patient's own cardiomyopathy mutation. (Technion - Israel Institute of Technology)
- Turns blood biomarkers, biometrics and nutrition data into an individual profile. (VII Technologies, Corp)
What are the latest personalized medicine innovations?
Over the past 90 days, researchers and innovators on Halo have added these personalized medicine solutions:
Which companies and suppliers are developing personalized medicine solutions?
There are 753 organizations with personalized medicine solutions on Halo, 106 of them universities and research institutions. Among them are Eascra, Massachusetts Institute of Technology, and University of Michigan. Most offer co-development or sponsored research. Sign up to see every organization working in the area and to send them your specific need.
How do I find personalized medicine research partners?
Browsing personalized medicine solutions on Halo is free. Sign up to search the full network and save the ones you want. Post your specific need to get exact matches. Organizations reply directly on the platform.
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