AA
Cornell University
A high internal phase emulsion holding fragrance oil and metering it out.
Co-developmentIn-development
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Updated Nov 2, 2026
Fragrance development covers holding a volatile compound in a product long enough to smell it. On Halo, the solutions cover structuring a formulation to hold scent, encapsulating a volatile, making the fragrance molecule, and predicting and controlling release. Sign up to search the full network and post your specific need.
Structuring a formulation to hold scent
AA
EC
University of British Columbia
Cellulose nanocrystals as emulsions, spray-dried powders and core-shell filaments.
Co-developmentIn-development
WJ
Innotech Materials, LLC · Supplier
Amphiphilic nanocellulose carrying scent and holding the intensity up.
Co-developmentIn-development
DR
FloZein Products · Supplier
A zein platform built for cough, cold and analgesic volatiles as much as perfume.
Co-developmentIn-development
Encapsulating a volatile
Francesco D'Acierno
Catholic University of Leuven (KU Leuven)
Electrostatic spray drying, and the result leaves no greasy residue.
Co-developmentIn-development
Marko Vincekovic
Makabi Agritech · Startup
Alginate microparticles releasing fragrance and essential oils slowly.
Co-developmentIn-development
James Oxley
Southwest Research Institute · University
Low temperature electrostatic spray drying, for volatiles in hostile environments.
Sponsored researchEarly-stage
Making the fragrance molecule
Rainer Wardenga
Aminoverse B.V. · Supplier
Novel enzymes making natural-grade lactones from renewable fatty acids.
Co-developmentIn-development
Akihiro Shimamoto
Mitsubishi Chemical Corporation · Supplier
Precision fermentation regenerating SAM, so methylated compounds come cheaper.
LicensingIn-development
MH
Oxford BioMedica · Supplier
Engineered P450 enzymes producing nootkatone and its derivatives.
LicensingEarly-stage
Predicting and controlling release
KS
Polymerize · Startup
Models the composition, rheology and volatility relationship together.
Co-developmentIn-development
Jerome Delhommelle
University of Massachusetts Lowell
Physics-informed prediction of how a fragrance mixture will behave.
Co-developmentEarly-stage
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Who is working on fragrance development
Organizations in fragrance development
Universities, startups, and suppliers with solutions in fragrance development.
Fragrance development companiesAbout fragrance development
Volatility is the entire problem on Halo. Seventeen entries slow a scent down in a topical product, using microcapsules, Pickering emulsions, liquid crystalline lipid matrices, zein, nanocellulose or a dual reservoir. A separate group makes the molecule itself with enzymes, where extraction would once have been the only route. On Halo it spans four groups, including structuring a formulation to hold scent, encapsulating a volatile, and making the fragrance molecule.
Stage of development. Work on fragrance development on Halo comes mostly from companies. 42% of the solutions are in market. Licensing and co-development are the usual partnering routes, and about 37% of the solutions that state terms offer supply and purchase.
Three trends in fragrance development on Halo
Seventeen ways to slow a molecule down. Microcapsules from hollow yeast cell walls, PEG-b-PLA micelles, alginate microparticles, electrostatic spray drying; and on the formulation side Pickering emulsions stabilized by flavonoids, a lyotropic liquid crystalline lipid matrix, zein, nanocellulose in three forms, and a dual reservoir giving impact then longevity. One problem, seventeen materials.
Topical, and often medicinal. Several entries name a cough suppressant, an analgesic or an OTC topical, and not a perfume. The same requirement drives both: a volatile applied to skin evaporates in minutes, and the product is judged on how long it lasts. Fragrance longevity research and OTC topical delivery turn out to be one field.
Enzymes making the molecule. Seven entries produce the fragrance compound itself, and four use biology to do it: engineered P450s for nootkatone, novel enzymes for natural-grade lactones, precision fermentation that regenerates SAM to make methylation cheap, and cell-free cascades running on an industrial waste stream. A natural-grade label and a synthetic cost are what these are chasing.
270organizations
292solutions listed
64%from startups and companies
42%in market
Frequently asked questions
What is fragrance development?
Fragrance development covers holding a volatile compound in a product long enough to smell it, and making the molecule in the first place. It spans encapsulation of volatiles, formulation chemistry that structures a scent into a topical, biocatalytic and fermentation routes to a fragrance molecule, and the prediction and release-control platforms around them. Fragrance houses and consumer goods manufacturers are the buyers.
What are examples of fragrance development?
Four examples of fragrance development solutions on Halo include:
- A high internal phase emulsion holding fragrance oil and metering it out. (Cornell University)
- Solvent-free PEG-b-PLA micelles taking a high fragrance oil load. (East Tennessee State University)
- Novel enzymes making natural-grade lactones from renewable fatty acids. (Aminoverse B.V.)
- Models the composition, rheology and volatility relationship together. (Polymerize)
What are the latest fragrance development innovations?
The most recently updated fragrance development solutions on Halo include:
Which companies and suppliers are developing fragrance development?
There are 270 organizations with fragrance development solutions on Halo, 49 of them universities and research institutions. Among them are Cornell University, University of British Columbia, and Innotech Materials, LLC. Most offer licensing or co-development. Sign up to see every organization working in the area and to send them your specific need.
How do I find fragrance development research partners?
Browsing fragrance development solutions on Halo is free. Sign up to search the full network and save the ones you want. Post your specific need to get exact matches. Organizations reply directly on the platform.
What are R&D teams looking for in fragrance development?
Over the past 12 months, R&D teams on Halo have posted these fragrance development needs:
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