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›Beauty & skincare›Biotechnology in cosmetics

Browse 686 solutions in biotechnology in cosmetics on the Halo network

Updated Sept 30, 2026

Biotechnology in cosmetics covers making a cosmetic ingredient with an organism. On Halo, the solutions cover proteins and peptides made by fermentation, biopolymers as the material, fermented ingredients replacing a commodity, and microbiome and postbiotic actives. Sign up to search the full network and post your specific need.

Proteins and peptides made by fermentation

KM

BioGrammatics

Non-Animal Collagen and Collagen-Supporting Protein Production Using Pichia pastoris

Engineered Pichia pastoris producing collagen with no animal involved.

Co-developmentIn developmentSupplier
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Defined Bioscience, Inc

Animal-free fermentation platform for precision collagen-supporting peptide ingredients

Recombinant precursors plus engineered proline hydroxylases, animal-free.

Co-developmentConceptualStartup
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EG

Renaissance BioScience

Yeast-based platform for sustainable peptide production

S. cerevisiae producing high-purity peptides at a cost that works.

In developmentStartup
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caykur

Plant-Based Bioactive Polypeptide Components for Collagen Support and Tissue Engineering

Plant polypeptides for collagen support, also producible by fermentation.

Co-developmentIn developmentStartup
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Zentraxa Ltd

Bespoke bio-inspired peptides for haircare applications

Adhesion motifs taken from marine molluscs, elastin and silk, bound to keratin.

Co-developmentIn developmentStartup
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NK

Enloq Foundry

Ai-native peptide design engine

Peptides generated computationally for cosmetic actives, not therapeutics.

Pilot or trial engagementIn developmentStartup
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DB

Bolt Threads

Functional vegan silk for inflammation reduction and active delivery in hair care

A vegan silk polypeptide forming a barrier and carrying ketoconazole through it.

In developmentStartup
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Biopolymers as the material

RM

Austrian Centre of Industrial Biotechnology

Cyanoflan: Versatile biomaterial for wound healing and skincare applications

A bacterial polymer with antioxidant and anti-inflammatory action built in.

In developmentUniversity
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FF

Universidade NOVA de Lisboa

FucoPol natural polysaccharide with photoprotective capacity for cosmetic and dermatological applications

A bacterial polysaccharide giving UVA and UVB protection at low loading.

Co-developmentIn developmentUniversity
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ZF

Arizona State University

Scalable biofabricated hydrocolloid patch platform using bacterial cellulose

Bacterial cellulose grown into a hydrocolloid lip patch, at industrial scale.

In developmentUniversity
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JD

Consulting-ai

PHAsil™-Sense Plus: Bio-PHA silicone-alternative oil gelator

A bio-based PHA copolymer offered in place of silicone elastomer, biodegradable.

Supply/purchaseIn developmentStartup
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SC

Chulalongkorn University

Biodegradable pH-responsive polyhydroxybutyrate micro/nanobeads

Polyhydroxybutyrate beads that open at a target pH, and biodegrade after.

In developmentUniversity
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NTP R&D Services Ltd

Electrospun Dissolving Nanofiber Delivery Platform for Skincare

Electrospun nanofiber film that dissolves the active onto the skin.

Co-developmentIn developmentStartup
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Who is working on biotechnology in cosmetics

Organizations in biotechnology in cosmetics

Universities, startups, and suppliers with solutions in cosmetic biotechnology.

Cosmetic biotechnology companies

Innovators in biotechnology in cosmetics

Researchers and inventors advancing cosmetic biotechnology.

Cosmetic biotechnology experts

About biotechnology in cosmetics

Collagen and peptides are where most of the work on Halo sits, produced by engineered Pichia, S. cerevisiae or designed from scratch by a model. Beside them are bacterial biopolymers used as the material itself, and a set of fermented ingredients written against a specific commodity. On Halo it spans five groups, including proteins and peptides made by fermentation, biopolymers as the material, and fermented ingredients replacing a commodity.

Stage of development. Work on biotechnology in cosmetics on Halo comes mostly from companies. 46% of the solutions are in market. Co-development and licensing are the usual partnering routes, and about 43% of the solutions that state terms offer supply and purchase.

Three trends in cosmetic biotechnology on Halo

Animal-free collagen, four ways. Engineered Pichia pastoris expressing collagen and its supporting proteins, recombinant precursors paired with engineered proline hydroxylases, S. cerevisiae producing peptides at cost, and a plant-derived polypeptide that can also be fermented. Animal-free is the requirement; which organism carries it is the open question.

The organism makes the material, not just the active. Six entries grow the substance itself. A bacterial polysaccharide with UVA and UVB protection at low loading, another with antioxidant action built into the polymer, bacterial cellulose grown into a lip patch, and a PHA copolymer offered in place of silicone elastomer. The biology is not producing an ingredient to formulate; it is producing the formulation.

Manufacturability is the bottleneck. Four entries do nothing for skin at all. A fusion protein architecture reaching 90% purity with no chromatography step, extremophile-inspired stabilization so cells and proteins store dry at ambient, large lipid bodies as a carrier past liposomes, and a platform for finding and stabilizing bioactive RNA. Biology that cannot be purified or shipped never becomes a cosmetic.

624organizations
686solutions listed
78%from startups and companies
46%in market

Frequently asked questions

What is cosmetic biotechnology?

Biotechnology in cosmetics covers making a cosmetic ingredient with an organism. It spans proteins and peptides produced by engineered yeast or designed computationally, biopolymers and biomaterials grown by bacteria, fermented ingredients offered in place of a commodity such as palm oil or a synthetic pigment, microbiome and postbiotic actives, and the purification and stabilization work that decides whether any of it can be manufactured.

What are examples of cosmetic biotechnology?

Five examples of cosmetic biotechnology solutions on Halo include:

  • Engineered Pichia pastoris producing collagen with no animal involved. (BioGrammatics)
  • A bacterial polymer with antioxidant and anti-inflammatory action built in. (Austrian Centre of Industrial Biotechnology)
  • Precision fermentation on agro-industrial waste, aimed at palm derivatives. (Terra Oleo)
  • An engineered postbiotic doing skin repair and antibacterial work at once. (Eligo Bioscience)
  • A fusion protein architecture reaching 90% purity with no chromatography. (Airobes, LLC)

What are the latest cosmetic biotechnology innovations?

The most recently updated cosmetic biotechnology solutions on Halo include:

  • 350 fermented oils in one searchable library, each one ready to scale. (SMEY)
  • Peptides generated computationally for cosmetic actives, not therapeutics. (Enloq Foundry)

Which companies and suppliers are developing cosmetic biotechnology?

There are 624 organizations with cosmetic biotechnology solutions on Halo, 61 of them universities and research institutions. Among them are BioGrammatics, Defined Bioscience, Inc, Renaissance BioScience, and caykur. Most offer co-development or licensing. Sign up to see every organization working in the area and to send them your specific need.

How do I find cosmetic biotechnology research partners?

Browsing cosmetic biotechnology solutions on Halo is free. Sign up to search the full network and save the ones you want. Post your specific need to get exact matches. Organizations reply directly on the platform.

What are R&D teams looking for in cosmetic biotechnology?

Over the past 12 months, R&D teams on Halo have posted these cosmetic biotechnology needs:

  • Hydrolysis and fermentation of biomass into cosmetic-grade fractions (September 2026)
  • Gene-to-ingredient recombinant proteins via vegan yeast fermentation (July 2026)

Related beauty & skincare research areas

Cosmetic chemistryNatural ingredients and formulationsDermatological treatmentsAnti-aging solutionsHair care technologySkin protection and sunscreensSustainable beauty productsFragrance developmentPersonal care analyticsBrowse all beauty & skincare solutions
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