Wearable aptalyzer for continuous hormonal monitoring in women's menstrual cycle

Overview

The Wearable Aptalyzer is an innovative technology designed to provide continuous and painless monitoring of estrogen and progesterone levels in women. Utilizing hydrogel microneedles for interstitial fluid collection and aptamer-based electrochemical biosensors, this wearable device is poised to revolutionize hormonal health tracking. By replacing glucose/lactate probes with hormone-specific aptamers, the Aptalyzer can deliver real-time insights into hormonal fluctuations, offering significant benefits for women managing menstrual health.

Technical specifications

• Hydrogel microneedles for painless interstitial fluid collection
• Aptamer-based electrochemical biosensors for specific detection of estrogen and progesterone
• Real-time biomarker tracking with a focus on hormonal health
• Integration involves attaching microneedles to the biosensor chip with a biocompatible adhesive
• Validation includes ex vivo testing on porcine skin and in vivo animal model studies

Technology readiness level

Currently at TRL 4, the Wearable Aptalyzer has undergone initial validation through in vivo studies for glucose and lactate monitoring, with plans for further adaptation and testing for hormonal monitoring in animal models.