Water-soluble chitosan for scalable health and commercial applications

Technology
In development
Company

Luna Labs offers a novel water-soluble chitosan formulation that resolves traditional solubility challenges, enabling its use in various health and commercial applications. This chitosan maintains cationic charge and biodegradability, with applications including hydrogels and coatings.

Overview

Luna Labs has developed an innovative water-soluble chitosan formulation that addresses solubility and processing challenges inherent to natural chitosan. This breakthrough allows for scalable applications in health and commercial industries. The chitosan maintains its cationic charge and biodegradability, providing natural antimicrobial and mucoadhesive properties. This formulation is soluble at physiological pH, eliminating the need for acidic processing, and can form ionic hydrogels for versatile applications in health and industrial sectors.

Technical specifications

Key features include:

  • Water solubility at physiological pH without acidic processing
  • Maintenance of cationic charge and biodegradability
  • Capability to form ionic hydrogels using tripolyphosphate (TPP)
  • Versatile applications as gels, films, coatings, or microbeads
  • Customizable for controlled-release delivery, skin adhesion, and as biodegradable exfoliants or surface-conditioning agents
  • Tunable mechanical and release properties by adjusting molecular weight and crosslink density
Technology readiness level

This water-soluble chitosan formulation has reached Technology Readiness Level 6. It has undergone validation in relevant environments, focusing on optimizing molecular weight and TPP crosslinking to achieve desired mechanical and release properties. Future validation plans include pilot-scale manufacturing and comprehensive biocompatibility and biodegradability testing in accordance with OECD and ISO guidelines.


About Luna Labs

Luna Labs is a product development company based in Charlottesville, Virginia, that creates specialized solutions for the defense, industrial, and healthcare sectors. The company leverages a multidisciplinary approach combining materials science, biotechnology, and systems engineering to solve complex technical challenges. By repurposing advanced technologies—such as adapting sol-gel chemistry for corrosion prevention or mimicking viral structures for drug delivery—Luna Labs develops breakthrough innovations. Their diverse portfolio includes advanced protective coatings, real-time asset monitoring systems, medical simulation training tools, and drug delivery platforms designed to improve human performance and safeguard critical infrastructure.

These technologies address significant real-world problems, such as enhancing the durability of military and aerospace assets through non-chromate corrosion control and providing medical professionals with realistic training ecosystems for hemorrhage control. By partnering with government agencies, defense contractors, and leading industrial organizations, the company focuses on advancing research from initial discovery through to commercial-scale implementation. Their commitment to innovation is evidenced by the successful deployment of their technologies in high-stakes environments and their ongoing development of platforms intended to address complex conditions like PTSD and traumatic brain injury.

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