Scalable biofabricated hydrocolloid patch platform using bacterial cellulose

Technology
In development
University

A scalable platform for producing biofabricated hydrocolloid lip patches using bacterial cellulose, offering excellent moisture retention and adhesion for cosmetic applications. Industrial outsourcing enables rapid scale-up while ensuring biocompatibility and stability.

Overview

This innovative platform utilizes bacterial cellulose (BC) to create biofabricated hydrocolloid lip patches that are biocompatible, breathable, and highly effective in moisture retention. The patches are designed for delicate lip skin, providing excellent adhesion for up to 8 hours. By outsourcing the fermentation of BC and focusing on the conversion process, the platform minimizes production risks and supports rapid scalability. The lip patches are infused with active ingredients such as hyaluronic acid and peptides, enhancing their cosmetic benefits.

Technical specifications

Key features:

  • Bacterial cellulose provides a clean-label, biodegradable hydrogel base
  • High water retention exceeding 90% ensures hydration
  • Adhesive-edge design allows patches to adhere for over 8 hours
  • Infusion of actives like hyaluronic acid enhances skin benefits
  • Conforms to ISO 10993 testing standards for biocompatibility
  • Supports 36-month stability under ICH Zone II conditions

Production Process:

  • Industrially sourced BC pellicles are optimized through thickness control and additive infusion
  • Heat sealing and pouching techniques are utilized for medical-grade adhesive borders and packaging
  • Tray-based or roll-fed formats support pilot-scale production
Technology readiness level

This platform is currently at Technology Readiness Level 4, with ongoing efforts to optimize production techniques and validate performance through biocompatibility testing and accelerated aging studies. The platform is preparing for a transition to commercial launch within 18 to 24 months.


About Arizona State University

Arizona State University is a comprehensive public research university with a multi-campus presence across the Phoenix metropolitan area and a scale that supports interdisciplinary, use-inspired discovery. Industry partners access co-located laboratories, a research and technology park, and innovation centers that house corporate teams with faculty to speed prototyping and validation. A formal alliance with a major hospital system and proximity to a fast-growing manufacturing corridor enable clinical translation and pilot-scale testbeds, while applied student engagements create dependable talent pipelines. Research is backed by competitive federal funding from agencies such as NSF, NIH, DOE, DOD, and NASA. A dedicated technology transfer office supports IP, licensing, and startup formation.

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