Sarmentosin: plant-based reversible MAO inhibitor for cognitive health
Sarmentosin, a plant-derived reversible MAO-A/B inhibitor from blackcurrant, offers a safe and effective boost to neurotransmitters without synthetic risks. Ideal for cognitive health products, it's clinically proven to enhance mood, alertness, and reduce mental fatigue.
Overview
Sarmentosin is a plant-derived, reversible MAO-A/B inhibitor extracted from blackcurrant. The compound is presented as providing acute improvements in alertness, mood, and mental fatigue by boosting neurotransmitters including dopamine, serotonin, and noradrenaline. The listing contrasts it with synthetic MAO inhibitors by stating it is clinically proven to avoid significant safety risks, positioning it for consumer products aimed at mental well-being. It is also described as scalable through natural extraction and precision fermentation, supporting potential use in beverages, supplements, and functional foods.
Technical specifications
Key features:
- Plant-derived reversible MAO-A/B inhibitor
- Clinically proven to boost dopamine, serotonin, and noradrenaline
- Enhances alertness, mood, and reduces mental fatigue
- Scalable natural extraction and precision fermentation pathways
- Heat stable in acidic beverages
Sarmentosin’s properties are presented as suitable for premium beverages, supplements, and functional foods targeting brain health and mental performance.
Technology readiness level
Sarmentosin is listed at Technology Readiness Level 6, indicating validation in relevant environments. Future development is described as including completion of toxicology tests, filing for GRAS status, and conducting follow-up human studies to support health claims.
About Ārepa
Arepa is a brain health company that develops functional beverages and supplements designed to support cognitive function, mental clarity, and neurological health. Its products are formulated using plant-based, caffeine-free ingredients, most notably its proprietary Neuroberry blackcurrant extract, alongside pine bark extract and L-theanine. The company emphasizes a scientific approach, working with neuroscientists to create formulations that are evaluated through independent human clinical trials to ensure safety and efficacy.
Focused on the intersection of nature, neuroscience, and food technology, the company aims to provide tools for improved mental performance in an increasingly demanding world. Their products, which include drinks, powders, and capsules, are marketed for various use cases ranging from performance enhancement to calm and clarity. The company has demonstrated traction by selling over one million bottles and maintaining a commitment to transparency by publishing peer-reviewed clinical research regarding their formulations.
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