Precision-tuned mushroom chitosan for enhanced gum health

Technology
In development
Company

This innovative solution utilizes mushroom-derived chitosan with controlled molecular weight to improve oral health. It optimizes mucoadhesion for gingival retention, provides sustained antimicrobial activity, and supports gum tissue repair. Additionally, it acts as a delivery system for active ingredients like stannous fluoride.

Overview

Precision-tuned mushroom chitosan is a groundbreaking innovation aimed at improving oral health through advanced chitosan technology. By controlling the molecular weight of chitosan derived from mushrooms, our solution enhances mucoadhesion, allowing it to adhere effectively to gum tissues. This results in prolonged antimicrobial action against gingivitis-causing pathogens and disruption of biofilms. Furthermore, its cationic charge ensures natural adherence to oral tissues, providing extended protection and improved mouthfeel. The chitosan also promotes wound healing, supporting gum tissue repair and regeneration. It serves as an effective delivery system for active ingredients like stannous fluoride and CPC, ensuring sustained release and improved bioavailability.

Technical specifications
  • Molecular weight control: Enables optimization of mucoadhesion and tissue penetration
  • Antimicrobial and anti-biofilm properties: Effective against pathogens like P. gingivalis and S. mutans
  • Wound healing: Supports gum tissue repair and regeneration
  • FDA GRAS status: Safe for oral care applications, free from shellfish allergens
  • Versatile format compatibility: Suitable for toothpaste, mouth rinse, and leave-on gel/film
  • Active delivery system: Enhances retention and sustained release of actives such as stannous fluoride and CPC
Technology readiness level

Currently at TRL 4, the solution has undergone early validation stages with in vitro studies supporting its efficacy. Future phases will focus on optimization, formulation development, and comprehensive efficacy and safety testing to further advance the technology for commercial applications.


About Chinova Bioworks

Chinova Bioworks (founded 2016) develops natural preservation and clarification agents from mushrooms. Its flagship product Chiber is an award-winning innovation turning mushroom waste into food-safe preservatives for global markets.

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