Patchless patch technology with z-pods for sustained topical agent release

Overview

Zylö Therapeutics presents an innovative solution in topical treatment delivery with its Patchless Patch technology, utilizing Z-pods. These amorphous silica particles enable a 24-hour sustained release of therapeutic agents directly from within the skin, providing significant advantages over traditional topical applications. By embedding deeply into the skin's stratum corneum and follicles, Z-pods ensure prolonged and effective delivery of anti-inflammatory, anti-microbial, or scar-reducing agents, enhancing treatment outcomes for conditions such as razor burns.

Technical specifications

Z-pods are versatile amorphous silica particles that integrate seamlessly into lotions, gels, and other topical formulations. Key features include:

• High encapsulation efficiency: Capable of loading 30-40% of most therapeutic agents.
• Deep skin embedding: Ensures agents are delivered from within the skin rather than on the surface.
• Proven efficacy: Demonstrated superior performance in head-to-head studies against neat applications, with successful market launches like Revive+ hair-densifying foam.
• Versatile application: Suitable for incorporating into or replacing traditional patches with options to combine with hydrocolloid materials for enhanced water retention and penetration.

Technology readiness level

This technology is at TRL 9, indicating it has been proven through successful deployment in operational environments. Products utilizing Z-pods are commercially available, and ongoing efforts are focused on expanding applications and international market reach.