Natural compounds that inhibit spoilage bacteria in food products
A technology offering proprietary natural, non-antibiotic compounds to inhibit spoilage bacteria and enhance shelf-life in food products such as meats and sauces. The compounds show in vitro activity against lactic acid bacteria (LAB) spoilage strains, including Lactiplantibacillus plantarum and Leuconostoc mesenteroides, at concentrations as low as 125 ppm. Future work includes validation for scalability and product stability, including shelf-life testing and performance under heat, pH, and solubility constraints in food matrices.
Overview
Proprietary natural, non-antibiotic compounds are developed to inhibit spoilage bacteria in food products, such as meats and sauces. The antimicrobial compounds are derived from secondary metabolites isolated from plants and wild-type bacterial and fungal strains. The objective is to enhance shelf-life by targeting specific lactic acid bacteria (LAB) spoilage strains, including Lactiplantibacillus plantarum and Leuconostoc mesenteroides, without resorting to antibiotics.
Technical specifications
Key features:
- Derived from natural plant sources and fermentation processes
- Effective against LABs at concentrations as low as 125 ppm
- Non-antibiotic, supporting safety and reduced resistance concerns
The compounds have demonstrated significant antimicrobial activity in vitro against spoilage strains relevant to the intended food applications, with plans for future shelf-life testing. Activity is confirmed and minimal inhibitory concentration (MIC) is determined using microbroth dilution assays. Additional tests include scalability, heat and pH stability, and solubility in food matrices.
Technology readiness level
This solution has reached Technology Readiness Level 5, with successful in vitro testing completed. The next stages include validation with specific spoilage strains and assessing practical applications in real food products.
About AnalytiCon Discovery GmbH
AnalytiCon Discovery is a research and development company specializing in natural product chemistry and small molecule compounds. Based in Potsdam, Germany, the company provides end-to-end services for the pharmaceutical, cosmetic, food, and agricultural sectors. Their capabilities span the entire discovery value chain, including the establishment of proprietary substance libraries, identification of active ingredients, synthetic optimization, and commercial-scale production. The company leverages an integrated approach that combines microbiology, natural product isolation, state-of-the-art analytical technologies like NMR and LC/MS, and advanced screening platforms. Since 2013, AnalytiCon has operated as a member of the BRAIN Biotech Group, utilizing specialized laboratories and a team of experts to transform natural molecules into viable, innovative products.
By offering deep expertise in natural product-based discovery, AnalytiCon serves as a critical partner for organizations seeking to overcome the complexities of medicinal chemistry and substance development. They solve significant industry challenges by providing high-quality, fully elucidated compound collections that expedite preclinical discovery projects and research into novel therapeutic targets. Their track record includes numerous successful collaborations with global pharmaceutical and consumer goods companies, focusing on applications such as drug discovery, sugar and calorie reduction, and natural preservation ingredients. Through their combination of technical competence and solution-oriented project management, they enable partners to accelerate the development of sustainable, bio-based products for diverse global markets.
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