Minimally invasive ion detection patch using ion-selective electrodes
A wearable, minimally invasive patch for rapid micronutrient monitoring using interstitial fluid (ISF). The device employs microneedles and ion-selective electrodes (ISEs) to detect electrolytes like Na+, K+, Mg+, and Zn+ in real-time, with results displayed via a mobile app.
Overview
This innovative solution offers a minimally invasive wearable patch for rapid and accurate monitoring of essential micronutrients. The device utilizes interstitial fluid (ISF) sampling, which closely mirrors blood plasma composition, providing reliable detection of key electrolytes such as sodium, potassium, magnesium, and zinc. By integrating ion-selective electrodes (ISEs) within a microfluidic channel, the solution ensures precise and real-time nutrient monitoring, delivering results within minutes through a connected mobile app. The patch is compact, user-friendly, and cost-effective, making it ideal for proactive nutritional management and mass-market adoption.
Technical specifications
- Microneedle-based ISF extraction: Painlessly extracts interstitial fluid from the dermis.
- Ion-selective electrodes (ISEs): Integrated into microfluidic channels for accurate detection of Na+, K+, Mg+, Zn+.
- Real-time results: Displayed through a mobile app, requiring no specialized training.
- Compact and easy to use: Simply apply the patch and view results instantly.
- Patent pending: Demonstrated detection with commercially available artificial ISF and proven miniaturization and sensor integration.
- Development roadmap: Includes selection of target ions, system integration, and mobile app enhancement.
Technology readiness level
The current technology readiness level is 3, indicating that the core components of the device have been validated in a laboratory environment. Future steps include further sensor validation, system integration, and clinical testing to progress towards higher readiness levels.
About Fraunhofer Institute
Fraunhofer is a large, multi-site applied research organization based in Germany, operating a nationwide network of institutes and research units with a strong industry-facing mission. Its contract-research model aligns work to real manufacturing and deployment needs, with pilot lines, test labs, and demonstration facilities for validation and scale-up. Many institutes are integrated with nearby universities and regional industry clusters, enabling joint appointments, shared infrastructure, and fast talent pipelines. Research is supported by competitive European programs alongside German federal and state funding, complemented by extensive contract revenue from private-sector collaborations. A dedicated technology transfer function manages IP, licensing, and startup formation.
delivered to your inbox.