Microparticle-based vaccines for spray, oral, and in ovo administration

Overview

Axilea LLC presents a cutting-edge solution for efficient and scalable vaccination in poultry using microparticle-based vaccines. These vaccines are designed to be administered via spray, oral, or in ovo methods, providing flexibility in mass vaccination strategies. The microparticles encapsulate vaccine components and act as adjuvants, ensuring effective immune responses without the need for high doses of additional adjuvants. The vaccines are also drinkable and compatible with subcutaneous injection, offering a robust and versatile vaccination platform.

Technical specifications

Key features:

• Microparticle Encapsulation: Vaccine components are encapsulated in microparticles, which themselves act as adjuvants.
• Environmentally Friendly: Made from succinate metabolite, the formulation is non-toxic and easily biodegradable.
• Flexible Administration Methods: Includes spray, oral (drinking water), and subcutaneous injection options.
• Room Temperature Stability: The vaccines can be stored at room temperature, reducing logistics costs associated with cold chain storage.
• One-Pot Synthesis: Ensures each dose contains all necessary components, enhancing consistency and efficacy.

Technology readiness level

The technology is at TRL 4, indicating that it has been validated in a laboratory setting. Future steps include scaling production, regulatory readiness, and in vivo efficacy testing in poultry to further advance this promising vaccination technology.