Microencapsulation of probiotics using polysaccharides and proteins
A novel microencapsulation method for probiotics using polysaccharides and proteins enhances pH and thermal resistance, ensuring probiotic viability in beverages and intestinal release. Suitable for improved probiotic formulations in functional foods.
Overview
Microencapsulation of probiotics using a combination of polysaccharides and proteins offers a groundbreaking method to enhance the stability and viability of probiotics. This innovative approach involves encapsulating probiotics in a matrix of weak acids (polysaccharides) and weak bases (proteins or protein hydrolysates) to provide superior protection against pH fluctuations and thermal stress. This technique is particularly beneficial for maintaining probiotic stability in acidic environments, such as beverages, and ensuring their effective release in the intestines.
Technical specifications
- Microencapsulation Matrix: Utilizes polysaccharides and proteins to act as acid scavengers, offering local pH buffering capacity.
- Stability: Improved resistance to pH and thermal conditions has been observed, making it suitable for various probiotic strains.
- Enteric Coating: Optional integration of enteric coating components ensures stability in gastric fluids and release in intestinal environments.
- Applications: Ideal for enhancing probiotic formulations in functional foods, particularly in beverages where stability is a concern.
Technology readiness level
Currently at Technology Readiness Level 4, this method has shown promising results in early-stage testing, especially with soil beneficial organisms. Plans are in place to validate the approach with selected probiotic strains through microencapsulation trials and stability testing, paving the way for further development and commercial application.
About Fraunhofer Institute
Fraunhofer is a large, multi-site applied research organization based in Germany, operating a nationwide network of institutes and research units with a strong industry-facing mission. Its contract-research model aligns work to real manufacturing and deployment needs, with pilot lines, test labs, and demonstration facilities for validation and scale-up. Many institutes are integrated with nearby universities and regional industry clusters, enabling joint appointments, shared infrastructure, and fast talent pipelines. Research is supported by competitive European programs alongside German federal and state funding, complemented by extensive contract revenue from private-sector collaborations. A dedicated technology transfer function manages IP, licensing, and startup formation.
delivered to your inbox.