Lateral flow assay for nutritional level detection using magnetic nanoparticles
A novel lateral flow assay enhanced with magnetic nanoparticles for detecting nutritional levels in urine and finger-prick samples with improved sensitivity and ease of use.
Overview
This innovative solution leverages lateral flow assay (LFA) technology, similar to that used in COVID-19 testing, to detect nutritional levels in urine and finger-prick samples. By integrating magnetic nanoparticles, this assay offers improved sensitivity, making it ideal for in-house or pre-clinic settings. The development aims to address the need for accessible, accurate nutritional monitoring.
Technical specifications
Key features:
- Utilizes magnetic nanoparticles to enhance sensitivity of detection
- Capable of detecting nutritional levels in both urine and finger-prick samples
- Designed to independently detect three specific nutrients, with plans for multiplex detection
- Aims to achieve a sensitivity of 0.01ng/mL
- Targets a true positive rate of over 90%
Technology readiness level
Currently at Technology Readiness Level 3, this solution is in the early stages of development. Prototypes are being developed to test individual and multiplex detection of nutrients, focusing on improving sensitivity and accuracy. Further validation is planned to optimize the assay’s performance and reliability.
About University of Wisconsin, Milwaukee
University of Wisconsin–Milwaukee is a comprehensive public research university in the state’s largest metro, pairing broad academic breadth with an applied, urban mission. Industry engages through an innovation campus and research park that co-locate university labs with startups and corporate teams, plus shared-use core facilities. Its location puts partners near a major regional medical center and within a leading freshwater and advanced manufacturing cluster, enabling pilots, internships, and joint development. Research is supported by competitive federal funding from agencies such as NSF, NIH, and DOE. A dedicated technology transfer office and affiliated foundation manage IP, licensing, corporate agreements, and seed funding to accelerate commercialization.
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