Home-use chemical sensors for small-volume biological fluids

Technology
In development
University

A novel sensor technology enabling accurate home-use assays with minimal biological fluid volumes. Detects ions like calcium, magnesium, zinc, and potentially vitamins using a microfluidic setup and colorimetric detection.

Overview

Our innovative technology offers a groundbreaking solution for home-based health monitoring by enabling accurate assays with just 1-3 microliters of biological fluids. This development is particularly beneficial for patients requiring frequent testing, as it minimizes discomfort and resource usage. Currently capable of detecting ionic species such as calcium, our technology promises to expand its application to other ions and nutrients, making it highly versatile for personalized health monitoring.

Technical specifications
  • Colorimetric Sensor: Utilizes an oil-based colorimetric method for precise ion detection.
  • Small Volume Requirement: Requires only 1-3 microliters of biological fluids like blood, urine, or saliva.
  • Ion Detection: Capable of detecting calcium ions with potential expansion to magnesium, zinc, and vitamins.
  • Multiplexed Sensing: Allows simultaneous detection of multiple analytes from a single sample.
  • Microfluidic Setup: Planned integration with a micro camera for enhanced detection accuracy in a home-use device.
Technology readiness level

The technology is currently at TRL 4, indicating it has been validated in a laboratory setting. Future development aims to create a user-friendly device for home use, with plans for patient testing in collaboration with partners once additional funding is secured.


About Virginia Commonwealth University

Virginia Commonwealth University is a comprehensive public research university and academic health center in Richmond, combining broad disciplinary breadth with a downtown, two‑campus footprint and top‑tier (R1) research activity. Integration with VCU Health enables large‑scale clinical research and translation, while shared core research facilities support collaborative, industry‑oriented R&D. Its urban location places faculty and students adjacent to the VA Bio+Tech Park and within a growing Mid‑Atlantic innovation corridor, and an optional engineering co‑op program creates a reliable talent pipeline for partners. Research is backed by competitive federal funding, including NIH and NSF. VCU TechTransfer and Ventures manages IP, licensing and startup formation.

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