Herbal extract solutions for skin disorder protection
Innovative herbal extracts from medicinal plants like Vitis vinifera and Cannabis sativa are being developed to address skin disorders. These extracts demonstrate antioxidant and enzyme inhibition effects, with in vitro and in silico studies to validate their efficacy.
Overview
The proposed research explores the development of herbal extracts from medicinal plants such as Vitis vinifera (grape) and Cannabis sativa (hemp) to combat skin disorders. These extracts are designed to offer protective benefits through antioxidant properties and enzyme inhibition, particularly targeting issues like hyperpigmentation. The research aims to validate the extracts' efficacy using cell-free models, in silico techniques, and in vitro experiments with cell lines.
Technical specifications
Key features:
- Extracts from Vitis vinifera and Cannabis sativa are analyzed for specialized metabolites.
- Antioxidant effects are measured using spectrophotometric assays.
- Anti-tyrosinase activity is evaluated to predict effects against hyperpigmentation.
- In vitro studies include analyzing CRH gene expression and norepinephrine levels in HypoE22 cells and cytokine gene expression in HaCaT cells.
- In silico techniques such as network pharmacology and docking are employed to propose mechanisms of action.
Technology readiness level
The technology is currently at TRL 3, indicating that active research is underway to validate its efficacy through laboratory studies, with a focus on understanding the biological and pharmacological impacts of these herbal extracts on skin health.
About Universita degli Studi Gabriele d'Annunzio di Chieti e Pescara
Università degli Studi “Gabriele d’Annunzio” Chieti–Pescara is a comprehensive public university serving the Abruzzo region, with two campuses and an affiliated teaching hospital. Co‑located clinical, preclinical, and analytical facilities enable industry to prototype, validate, and scale with academic partners. The university maintains structured pathways for collaboration, including sponsored research, contract services, student placements, and tailored short courses coordinated through central liaison offices. Research draws on competitive European and Italian support, including Horizon Europe, national ministries, and regional innovation programs. A dedicated technology transfer office manages IP, licensing, spin‑outs, and collaboration agreements, and helps companies access shared instrumentation.
Inquire about this partnering listing
Industry applications
delivered to your inbox.