Exhaled breath biomarkers for physiological and behavioral reactions to products
A non-invasive, handheld device for sampling exhaled breath condensate (EBC) and saliva to measure physiological responses to consumer products. Enables quantification of biomarkers like cortisol and amylase, facilitating consumer product testing and social bonding analysis.
Overview
This innovative solution utilizes exhaled breath condensate (EBC) and saliva droplet sampling to non-invasively measure physiological and behavioral reactions to consumer products. The device is designed to be used by individuals in various settings, such as focus groups or home environments, to quantify biomarkers like cortisol and amylase. These biomarkers can indicate stress levels and social bonding responses to product exposure, offering valuable insights into consumer behavior and product effectiveness.
Technical specifications
Key features:
- Handheld, battery-powered sampler for user-friendly operation
- Simultaneous collection of EBC and saliva droplets
- Non-invasive sampling, eliminating the need for blood draws
- Storage of samples in a home freezer for later laboratory analysis
- Capable of real-time measurement of exhaled breath metabolomic content, such as volatile organic compounds (VOCs)
Technology readiness level
Currently at Technology Readiness Level 3, the device has been validated in laboratory settings and is backed by four issued patents. Future validation plans include partnering with industry leaders like P&G to further test and refine the device for market-ready applications.
About University of California, Davis
UC Davis is a comprehensive public research university in Northern California, combining a land-grant heritage with an integrated academic health system and a veterinary teaching hospital. Industry engages through co-located clinical and translational facilities in Sacramento, a campus-adjacent research park, pilot-scale food and bioprocessing facilities, and a statewide extension network for field-to-market deployment. Proximity to the Bay Area and California's Central Valley enables rapid collaboration with startups and established enterprises, while corporate relations staff streamline access to faculty, talent, and core labs. Research is supported by competitive federal funding from agencies such as NIH, NSF, USDA, and DOE. A dedicated technology transfer office and venture support programs provide IP management, licensing, and startup formation pathways for industry partnerships.
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