Engineered postbiotic platform with skin repair and antibacterial properties

Overview

The engineered postbiotic platform developed by Eligo Bioscience offers a cutting-edge solution for skin repair and antibacterial applications. This novel technology is designed as a multi-functional ingredient that can be incorporated into various skin products, such as hydrocolloidal patches. It leverages the synergistic properties of engineered postbiotics for effective wound healing and targeted antibacterial effects, making it highly suitable for dermato-cosmetic and therapeutic uses.

Technical specifications

The platform utilizes a GRAS (Generally Recognized As Safe) probiotic that is engineered, fermented, and lysed to produce the desired effects. With in vitro and ex vivo proof of concept data, this technology demonstrates its capability to modulate specific functions and mechanisms of action (MoAs) within the ingredient. The ongoing development aims to integrate the postbiotic into hydrocolloidal patches, promising enhanced stability and effectiveness for conditions such as atopic dermatitis and shave burns. Current stability data shows promising results with a 6-month buffer stability.

Technology readiness level

The postbiotic platform is currently at Technology Readiness Level 4. It has been validated in laboratory settings with in vitro and ex vivo data. Further development and partnership are sought for formulation into hydrocolloidal patches and broader commercial applications.