Covalent peptide-based keratin reinforcement platform for damaged hair fibers
A biomimetic keratin repair platform designed to restore the mechanical strength and structural integrity of damaged hair fibers through keratin-binding peptides, thiol-reactive crosslinking agents, and targeted nanoemulsion delivery systems.
Overview
The Covalent Peptide-Based Keratin Reinforcement Platform offers a revolutionary approach to repairing damaged hair fibers by mimicking nature's own processes. Unlike traditional conditioners that merely coat the surface, this platform targets the internal structure of the hair at the molecular level, facilitating deep and lasting repair. By focusing on key issues such as broken disulfide bonds and weakened protein networks, this solution promises enhanced strength, elasticity, and structural integrity for hair damaged by bleaching, heat, and mechanical stress.
Technical specifications
Key components and features:
- Keratin-binding peptides: Selectively associate with damaged hair regions to support protein reorganization and reduce crack propagation.
- Thiol-reactive crosslinking agents: Rebuild weakened disulfide networks within keratin structures, enhancing the hair's structural resilience.
- Targeted nanoemulsion/liposomal delivery systems: Ensure deep penetration into the hair cortex for prolonged repair effects.
The platform leverages cosmetic-compatible ingredients, making it suitable for commercial formulations. Analytical methods, including tensile testing, DSC, FTIR, and SEM, will be employed to validate performance, safety, and structural reinforcement capabilities.
Technology readiness level
Currently at Technology Readiness Level 3, this platform is in the proof-of-concept phase. Over 3-6 months, the project will progress through peptide and agent selection, prototype formulation, and rigorous testing to establish the technical feasibility of a scalable deep keratin repair solution.
About University of British Columbia
UBC is a comprehensive public research university with major campuses in Vancouver and the Okanagan, among Canada’s largest and most internationally connected. Industry engages through a co-op talent pipeline and collaborative research spaces that include co-located clinical settings and on‑campus testbeds. A dedicated technology transfer office brokers partnerships, manages IP and licensing, and is complemented by an active venture accelerator and incubator network. Research is supported by competitive funding from Canada’s Tri‑Council agencies (NSERC, CIHR, SSHRC) and infrastructure investments from the Canada Foundation for Innovation, alongside provincial and industry sponsorship.
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