Comprehensive database of annotated microbial natural products for drug discovery partnerships
A proprietary natural product discovery platform with over 200 structurally annotated microbial natural product entities, offering unique molecular diversity for pharmaceutical and biotechnology research and development partnerships.
Overview
This offering presents a comprehensive, proprietary database of microbial natural products (NPs) developed through a specialized natural product discovery approach. The collection provides access to more than 200 entities with complete structural annotation, representing a valuable resource for organizations seeking novel molecular scaffolds for drug discovery, lead optimization, and bioactive compound development. Natural products remain one of the most productive sources of pharmaceutical leads, and structurally characterized microbial metabolites offer distinct chemical diversity that is difficult to replicate through synthetic chemistry alone.
Technical specifications
- Proprietary discovery platform: A specialized screening approach designed for the isolation and characterization of microbial natural products
- Extensive collection: Over 200 structurally annotated entities derived from curated microbial collections
- Complete structural annotation: Each compound in the database has been fully characterized at the structural level, enabling immediate evaluation for research and development purposes
- Microbial sourcing: Compounds are isolated from diverse microbial organisms, providing broad chemical space coverage
- Research-ready data: Structural information is available to support downstream applications including bioactivity screening, medicinal chemistry optimization, and target identification
Technology readiness level
The database has been developed and curated through ongoing research at the University of Michigan, with compounds isolated and characterized through the proprietary screening approach. The collection is available for partnership engagement, with the molecular entities and their structural data ready to support collaborative research, licensing discussions, and co-development activities with industry partners in the pharmaceutical, biotechnology, and agrochemical sectors.
About University of Michigan
The University of Michigan is a comprehensive public research university based in Ann Arbor with additional campuses in Dearborn and Flint, known for a broad, interdisciplinary research enterprise and a major academic health system. Industry partners engage through co-located facilities, including a large north campus research complex with shared labs and incubator space, plus on-campus testbeds for rapid prototyping and validation. Proximity to Detroit’s mobility and manufacturing base, plus dedicated business engagement teams, streamlines sponsored research and access to talent. Research is supported by competitive federal funding from agencies such as NIH, NSF, DOE, and DoD, alongside state and industry sponsorship. A centralized tech transfer office manages IP, licensing, and startup support, with corporate memberships and flexible agreements.
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