Cocoa stem cell flavanols for mitochondrial and skin health

Overview

California Cultured has developed an advanced cell-based cocoa flavanol ingredient that significantly enhances beauty and longevity by targeting key aging hallmarks. This ingredient, rich in bioavailable (-)-epicatechin, activates the SIRT1/PGC-1α pathway, promoting mitochondrial biogenesis and protecting the skin from UV-induced damage. It also improves structural beauty by stimulating nitric oxide, enhancing microcirculation, and protecting collagen from oxidative stress. Cultivated in bioreactors, this technology offers a 20x higher flavanol concentration compared to traditional cacao and is free from soil-related contaminants, ensuring a clean and sustainable beauty solution.

Technical specifications

• Bioactive Compound: High concentration of (-)-epicatechin
• Mechanism: Activates SIRT1/PGC-1α pathway for mitochondrial biogenesis
• Benefits: Enhances skin, hair, and nail vitality by improving microcirculation
• Cultivation: Grown in bioreactors to avoid heavy metals and provide a climate-resilient supply chain
• Regulatory Compliance: Self-affirmed US GRAS status for smooth integration into ingestible beauty products

Technology readiness level

This innovative ingredient is currently at Technology Readiness Level 6, indicating that it has been demonstrated in a relevant environment and is moving towards commercial readiness. The ongoing validation includes formulation, pilot studies, and preparation for market launch.