Cardiovascular research core: preclinical cardiovascular models & functional assessment
Preclinical rodent cardiovascular disease models with echocardiography, hemodynamics, and functional assessment. Partners can run studies core-assisted or self-directed, covering heart failure, hypertension, stroke, and lung injury.
Overview
The Cardiovascular Research Core, part of UIC's Research Resources Center, provides rodent cardiovascular disease models and functional assessment for preclinical research and drug-efficacy testing. Partners can run studies self-directed or core-assisted, covering heart failure, hypertension, pulmonary hypertension, stroke, and lung injury.
Available services
- Rodent disease models (heart failure, hypertension, pulmonary hypertension, stroke, lung injury)
- Echocardiography and electrocardiography
- Blood-pressure and hemodynamic measurement
- In-vivo optical imaging
- Drug-delivery and efficacy studies
- Grant and protocol consultation
- Two engagement modes: core-assisted or self-directed
Equipment & instruments
- FUJIFILM VisualSonics Vevo 2100 — high-frequency ultrasound for rodent echocardiography
- Mouse Specifics ECGenie — non-invasive conscious-rodent electrocardiography
- Kent Scientific CODA — non-invasive tail-cuff blood-pressure system
- PerkinElmer IVIS Spectrum — in-vivo optical (bioluminescence/fluorescence) imaging
- Hemodynamic measurement instrumentation
Access & booking
UIC and external researchers schedule instrument time through UIC iLab (uic.ilab.agilent.com); new services require contacting the core. Internal rates extend to Northwestern and University of Chicago users. All work requires prior IACUC-approved animal protocol.
Location
835 S. Wolcott Ave, M/C 937, Chicago, IL 60612.
About University of Illinois Chicago
UIC researchers are advancing discoveries across the life sciences, engineering, computer science, energy, manufacturing, public health, biomedical and other fields. Our scientists are supported by funding from the National Institutes of Health, National Science Foundation, U.S. Department of Energy, and other federal agencies.
Through UI Health, UIC offers a major academic health system with deep expertise in translational research, clinical trials, health information sciences and community-engaged healthcare. Beyond campus, UIC collaborates extensively with industry, other universities, national laboratories, government agencies, healthcare systems, and nonprofit organizations to translate research into real-world impact. From cutting-edge core facilities and specialized research infrastructure to world-class faculty and interdisciplinary research centers, UIC provides partners with access to a uniquely urban innovation ecosystem designed to accelerate discovery, commercialization and societal benefit.
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