SYNGI is a specialized deep-tech hardware startup operating at the intersection of advanced semiconductor engineering, Multiphysics computational modeling, and acoustic micro-electro-mechanical systems (MEMS). Our fundamental mandate is to dismantle the physical and manufacturing bottlenecks that have historically restricted high-resolution mass sensing to laboratory environments. We are the developers of the Zero-TCE (ZTCE) architecture: a proprietary, solid-state platform engineered to bypass the extreme limitations of traditional hollow-core microchannel resonators. By replacing fragile microfluidic tubes with a fully solid-state array, SYN.G.I has established a viable, CMOS-compatible pathway to ambient, label-free mass profiling at the zeptogram scale, directly in native liquid.