PZ
Immersion Neuroscience · Startup
Neurological measurement of engagement, run at population scale.
LicensingIn-development
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Receive a weekly email digest of the latest mental wellness solutions added by the network.Browse 137 solutions in mental wellness solutions on the Halo network
Updated Nov 2, 2026
Mental wellness solutions covers measuring a mental state, and acting on it outside a clinic. On Halo, the solutions cover measuring a mental state, therapy delivered through a device, and botanical and nootropic actives. Sign up to search the full network and post your specific need.
Measuring a mental state
PZ
YM
Aptasensors in a buccal prosthetic tracking cortisol and oxytocin live.
Sponsored researchIn-development
Anup Sharma
Keystone Neuroinformatics · Startup
Clinical evaluation and quantitative validation for mental health platforms.
Co-applicantIn-development
Therapy delivered through a device
UO
University of Tennessee, Knoxville
Cognitive behavioral therapy for major depression delivered by text.
LicensingIn-development
Manob Saikia
University of Memphis
Heart rate variability breathing delivered as a digital therapy.
Sponsored researchEarly-stage
Dan Gardner
ExpertFocus LLC · Startup
An adaptive offline-first audio application built for infant sleep.
LicensingIn-development
Paul Arciero
Nootropic supplementation paired with an app, for cognitive resilience.
Sponsored researchEarly-stage
Botanical and nootropic actives
Angus Brown
Sarmentosin, a plant-derived reversible MAO inhibitor for cognition.
In-development
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Who is working on mental wellness solutions
Innovators in mental wellness solutions
Researchers and inventors advancing mental wellness solutions.
Mental wellness expertsAbout mental wellness solutions
Mental wellness on Halo splits evenly into three. Four entries measure a state, through neurological, biochemical or digital-twin means. Four deliver an intervention, through text, audio or an app. Two are ingestible actives. The measurement work sits closest to sleep and circadian research, which is the neighboring field this one borders most. On Halo it spans three groups: measuring a mental state, therapy delivered through a device, and botanical and nootropic actives.
Stage of development. Work on mental wellness solutions on Halo is split between university programs and companies. 46% of the solutions are in market. Sponsored research and co-development are the usual partnering routes, and about 33% of the solutions that state terms offer pilot engagements.
Three trends in mental wellness solutions on Halo
Chemistry aimed at cognition. Two entries approach mental wellness as a chemistry problem. One is sarmentosin, a plant-derived reversible MAO inhibitor put forward for cognition; the other pairs a nootropic supplement with an app that tracks whether it is working. Pairing a compound with a way to measure it is what both have in common, and it is what separates them from a supplement sold on its label alone.
Delivery is text, audio and app. Cognitive behavioral therapy delivered entirely by text message for major depression, heart rate variability breathing as a digital therapy, an offline-first audio application for infant sleep, and nootropic supplementation paired with an app. None of the four requires a therapist to be present, which is the constraint they are all built around.
Measurement aimed at a population, not a patient. Neurological measurement of engagement at scale, aptasensors tracking cortisol and oxytocin continuously, a digital twin of emotional and cognitive state, and a validation service for mental health platforms. The last one is the tell: enough products now claim a mental health effect that validating the claim is itself a business.
143organizations
137solutions listed
56%from startups and companies
46%in market
Frequently asked questions
What are mental wellness solutions?
Mental wellness solutions covers measuring a mental state and acting on it outside a clinic. It spans neurological and biochemical measurement of engagement and stress, therapy and support delivered through text, audio or an app, and the botanical and nootropic actives aimed at cognition and mood. Consumer health brands, employers and clinical teams are the buyers.
What are examples of mental wellness solutions?
Three examples of mental wellness solutions on Halo include:
What are the latest mental wellness innovations?
The most recently updated mental wellness solutions on Halo include:
Which companies and suppliers are developing mental wellness solutions?
There are 143 organizations with mental wellness solutions on Halo, 22 of them universities and research institutions. Among them are Immersion Neuroscience, Rice University, and Keystone Neuroinformatics. Most offer sponsored research or co-development. Sign up to see every organization working in the area and to send them your specific need.
How do I find mental wellness research partners?
Browsing mental wellness solutions on Halo is free. Sign up to search the full network and save the ones you want. Post your specific need to get exact matches. Organizations reply directly on the platform.
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