Electrostatic spray-dried postbiotics-prebiotics for oral microbiome balance

Overview

The innovative solution of electrostatic spray-dried postbiotics-prebiotics focuses on enhancing oral health by modulating the microbiome. Developed through a cutting-edge electrostatic spray drying (ESD) process, this system co-encapsulates selected postbiotics and prebiotic substrates within a food-grade polysaccharide matrix. The microcapsules, sized between 10-50 µm, are designed for incorporation into oral care products such as toothpaste and mouthwash. Upon use, the system releases actives through controlled hydration, which enriches beneficial oral microbes and buffers pH levels, thereby reducing the risk of gingivitis.

Technical specifications

• Electrostatic Spray Drying (ESD): Utilizes low-temperature processing to preserve bioactivity and ensure high encapsulation efficiency.
• Microcapsules: Composed of postbiotics and prebiotics like arginine and inulin, encapsulated in maltodextrin-gum arabic.
• Release Mechanism: Controlled hydration in the mouth triggers active release, enhancing microbiome balance without disturbing the ecosystem.
• Compatibility: Suitable for integration into common oral care products, scalable, and cost-effective.

Technology readiness level

Currently at Technology Readiness Level 3, this solution is in the experimental proof of concept stage. Future validation phases will include ingredient selection, function proof via in vitro models, stability and safety studies, and prototype development for oral-care formats.