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Robert Screaton

Principal Investigator

Sunnybrook Health Sciences Centre

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8 months ago

Mitochondria, Cellular Metabolism, Redox Signaling, Aging

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Research explores how mitochondrial dynamics and redox signaling govern cellular bioenergetics, stress responses, and cell fate. Genetic models link mitochondrial reserve capacity to insulin secretion, cardiac remodeling, and age-related declines in metabolic function.

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Sunnybrook Health Sciences Centre

Targeted ROMO1 modulation for treating obesity and type 2 diabetes

A novel approach targeting ROMO1, a mitochondrial protein, to treat metabolic disorders. Inhibiting ROMO1 in the liver promotes weight loss, while activating it in pancreatic beta cells supports glucose management, preve...

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Robert Screaton

Principal Investigator

Sunnybrook Health Sciences Centre

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Sunnybrook Health Sciences Centre

Principal Investigator

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Last updated Jan 2026