
Research platform investigating how caffeine activates the ADORA2A receptor in brain endothelial cells to enhance blood-brain barrier transport of nootropics such as insulin. Leverages established expertise in BBB transp...
Research platform investigating how brain insulin receptor signaling regulates neuroinflammation in Alzheimer's disease. Preliminary data show that acute blockade of brain insulin receptors reduces blood-brain barrier pe...
A sensitive method for measuring the brain uptake of appetite-suppressing compounds, enabling the identification of effective candidates for obesity therapy. It employs radiolabeled substrates to track transport across t...