We have developed new additives to the cell culture media that accelerate the metabolism of T cells that are being generated for CAR T cell therapy. These materials also can be used to accelerate metabolism of other cel...
Innovative poly(alpha-ketoglutarate) nanoparticles control intracellular metabolite ratios in immune cells, inducing immunosuppressive responses. Validated in rheumatoid arthritis models, these nanoparticles target multi...